Rheumatoid Arthritis Statpearls (2024)

1. Rheumatoid Arthritis - StatPearls - NCBI Bookshelf

• Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammatory arthritis and extra-articular involvement.

• Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammatory arthritis and extra-articular involvement. It is a chronic inflammatory disorder caused in many cases by the interaction between genes and environmental factors, including tobacco, that primarily involves synovial joints.[1] It typically starts in small peripheral joints, is usually symmetric, and progresses to involve proximal joints if left untreated.[2][3][4] Joint inflammation over time leads to the destruction of the joint with loss of cartilage and bone erosions. RA with a symptom duration of fewer than six months is defined as early RA, and when the symptoms have been present for more than six months, it is defined as established RA.[3] RA, if untreated, is a progressive disease with morbidity and increased mortality.[5]

2. Arthritis - StatPearls - NCBI Bookshelf

• 20 jun 2023 · Rheumatoid arthritis is found in approximately 1% of Caucasians, with females being affected more frequently than males (lifetime risk of 3.6% ...

• Arthritis is derived from the Greek term “disease of the joints.” It is defined as an acute or chronic joint inflammation that often co-exists with pain and structural damage. [1] Arthritis is not synonymous with arthralgia, which refers to pain localized to a joint, regardless of the origin of the pain (which may or may not be due to joint inflammation). Arthritis affected both the Neanderthals and ancient Egyptians, but It was not until 1886 that Dr. John K. Spencer coined the term “osteoarthritis.” More than 100 different types of arthritis have been described, the most common being osteoarthritis or degenerative arthritis which is non-inflammatory arthritis. Inflammatory arthritis can occur in several settings, and inflammation can be caused by autoimmune processes (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, etc.), crystal deposition induced inflammation (gout, pseudogout, basic calcium phosphate disease) or infections (septic arthritis, Lyme's arthritis).  Inflammatory arthritis can also accompany other autoimmune connective tissue diseases such as systemic lupus erythematosus, Sjogren syndrome, scleroderma, myositis, inflammatory bowel disease, celiac disease, etc. 

3. Rheumatoid Arthritis | StatPearls | Treatment & Management

• Rheumatoid arthritis is a systemic and chronic inflammatory state caused by an autoimmune response to an environmental trigger.

• Rheumatoid Arthritis

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4. Hand and Wrist Rheumatoid Arthritis | Treatment & Management - StatPearls

• 17 aug 2023 · Inflammatory arthritis involving the small joints of the hands is the most common initial presentation in rheumatoid arthritis.

• Point of Care - Clinical decision support for Hand and Wrist Rheumatoid Arthritis. Treatment and management. Introduction, Etiology, Epidemiology, Pathophysiology, Histopathology, History and Physical, Evaluation, Treatment / Management, Differential Diagnosis, Prognosis, Complications, Deterrence and Patient Education, Enhancing Healthcare Team Outcomes

5. Moderate active Rheumatoid arthritis | StatPearls | Treatment & Management

• Rheumatoid Arthritis. Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammatory arthritis and extra-articular involvement.

• Moderate active Rheumatoid arthritis

6. Juvenile Idiopathic Arthritis | StatPearls | Treatment & Management

• Inflammatory arthritis involving the small joints of the hands is the most common initial presentation in rheumatoid arthritis. Introduction · Etiology ...

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• Juvenile Idiopathic Arthritis

7. A Review of Rheumatoid Arthritis for Pharmacists

• 18 nov 2022 · Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of synovial tissue in the joints that results in joint pain and ...

• US Pharm. 2022;47(11):36-71.

8. Systemic complications of rheumatoid arthritis: Focus on pathogenesis ...

• As a systemic autoimmune disease, rheumatoid arthritis (RA) usually ... In: StatPearls. Treasure Island (FL: StatPearls Publishing (2022). Google ...

• As a systemic autoimmune disease, rheumatoid arthritis (RA) usually causes damage not only to joints, but also to other tissues and organs including the hear...

9. The Approach to the Painful Joint: Overview, Pathophysiology, Clinical ...

• 30 mei 2024 · Joint pain may arise from structures within or adjacent to the joint or may be referred from more distant sites. Sources of pain within the ...

• Joint pain can have multiple causes, a reflection of the diverse joint diseases, which arise from inflammation, cartilage degeneration, crystal deposition, infection, and trauma. The initial aim of the evaluation of a patient with joint pain is to localize the source of the joint symptoms and to determine the type of pathophysiologic process ...

10. Rheumatoid Arthritis and Ankylosing Spondylitis | Point of Care - StatPearls

• 4 aug 2023 · Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are among the most common rheumatic diseases. These chronic progressive ...

• Point of Care - Clinical decision support for Rheumatoid Arthritis and Ankylosing Spondylitis. Treatment and management. Introduction, Etiology, Epidemiology, Pathophysiology, History and Physical, Evaluation, Treatment / Management, Differential Diagnosis, Prognosis, Consultations, Pearls and Other Issues, Enhancing Healthcare Team Outcomes